[mysqld]
max_connections=900
max_user_connections=50
skip-locking
skip-innodb
query_cache_limit=1M
query_cache_size=32M
query_cache_type=1
interactive_timeout=50
wait_timeout=50
connect_timeout=10
thread_cache_size=128
key_buffer=256M
max_allowed_packet=16M
table_cache=1024
join_buffer=1M
sort_buffer_size=1M
read_buffer_size=1M
max_connect_errors=10
thread_concurrency=4
myisam_sort_buffer_size=64M
log-bin
server-id=1

[safe_mysqld]
open_files_limit=8192

[mysqldump]
quick
max_allowed_packet=16M

[mysql]
no-auto-rehash
[isamchk]
key_buffer=64M
sort_buffer=64M
read_buffer=16M
write_buffer=16M

[myisamchk]
key_buffer=64M
sort_buffer=64M
read_buffer=16M
write_buffer=16M

[mysqlhotcopy]
interactive-timeout

Then
/etc/rc.d/init.d/mysql stop;
/etc/rc.d/init.d/mysql start;